Regenerative Medicine, Emerging Techniques to Translation Nishant Chakravorty, Praphulla Chandra Shukla 2023

Regenerative Medicine, Emerging Techniques to Translation Nishant Chakravorty, Praphulla Chandra Shukla 2023

Introducing Regenerative Medicine: Emerging Techniques to Translation Approaches (2023)

「Editors」: Dr. Nishant Chakravorty & Dr. Praphulla Chandra Shukla 

「Publisher」: Springer Nature Singapore (1st ed. 2023), 390 pages

Overview & Significance

The field of regenerative medicine stands at the forefront of modern bioscience, offering transformative strategies to restore, regenerate, and replace damaged tissues and organs. This meticulously curated volume—Regenerative Medicine: Emerging Techniques to Translation Approaches—provides an authoritative and comprehensive exploration of both foundational principles and frontier technologies. It is indispensable reading for advanced students, researchers, and clinicians seeking depth, breadth, and translational relevance.

Co-edited by Dr. Nishant Chakravorty and Dr. Praphulla Chandra Shukla—both esteemed faculty at the Indian Institute of Technology, Kharagpur—the book benefits from the rich research pedigrees and interdisciplinary perspectives of its editors.

Editors’ Credentials

  • 「Dr. Nishant Chakravorty」 leads a regenerative medicine laboratory at IIT Kharagpur. A physician–scientist and PhD graduate (Queensland University of Technology), his expertise spans cellular/molecular biology, biomaterials, and tissue engineering. He has an impressive publication record, editorial board roles, and is affiliated with international scientific academies.
  • 「Dr. Praphulla Chandra Shukla」, also of IIT Kharagpur, brings deep expertise in myocardial regeneration, endothelium biology, cardiomyocyte cell cycle regulation, and epigenetics. His postdoctoral and research experience spans institutions such as Charité Berlin, Boston University, and University of Toronto.

Their complementary credentials ensure a well-rounded and authoritative editorial framework.

Structure & Thematic Coverage

Spanning 16 meticulously crafted chapters, the volume delves into both mechanistic foundations and translational innovations across diverse regenerative strategies:

  1. 「Regeneration & Tissue Microenvironment」
  2. 「Non-Stem Cell Mediated Repair」
  3. 「Immunological Perspectives in Tissue Engineering」
  4. 「Advances in Medical Imaging for Wound Repair」
  5. 「Biosensors in Regenerative Therapeutics」
  6. 「Acute & Chronic Wound Management」
  7. 「Stem Cells in Cardiac Regeneration」
  8. 「Hydrogel-Based Tissue Mimics for Vascular Regeneration」
  9. 「Advances in 3D Printing for Tissue Engineering」
  10. 「Adult Neurogenesis as a Target」
  11. 「Regenerative Approaches in the Nervous System」
  12. 「Prenatal Interventions for Congenital Disorders」
  13. 「LncRNAs in Biomaterials for Osteointegration」
  14. 「Vertical Bone Augmentation and Orofacial Regeneration」
  15. 「Tracking Cell–Biomaterial Interactions (Bone Regeneration)」
  16. 「RNAs and Oncogenic Pathways in Cancer & Regeneration」

Core Features & Highlights

1. Stem Cells, Biomaterials & Tissue Microenvironment

The book delivers a robust introduction to the interplay between stem cells (including non-stem approaches), biomaterials, and the microenvironment—emphasizing how these elements synergize in tissue repair and regeneration.

2. Technological Innovation

Sophisticated techniques are covered, such as:

  • 「Medical Imaging & Biosensing」: Tools for real-time monitoring and therapeutic alignment; organ-on-a-chip platforms for translational modeling.
  • 「3D Printing & Hydrogels」: Engineered scaffolds and biomimetic niches enabling vascularization and structural fidelity.

3. Systems-Level Regeneration

Explores regenerative interventions in:

  • 「Cardiovascular Systems」, via stem-cell therapies and biomaterial scaffolds.
  • 「Neural Tissue」, focusing on neurogenesis and central nervous system repair.
  • 「Bone and Orofacial Tissues」, including LncRNA-based osteointegration and vertical bone augmentation strategies.

4. Translational Relevance

The inclusion of wound healing, monitoring techniques, and prenatal interventions grounds the research in practical clinical applications. Researchers aiming to bridge basic science and patient care will find this approach especially valuable.

Contextual Advances in Regenerative Medicine

To appreciate the book’s contributions, consider these contemporary advances:

  • 「3D Bioprinting」: Successful reconstruction of organs, such as bladders, with long-term viability; potential applications in bone, cartilage, and muscle tissue repair.
  • 「Nano-Scaffolding」: Biomimetic, degradable structures supporting stem cell integration and enhanced regeneration at cellular scales.
  • 「Induced Pluripotent Stem Cells (iPSCs)」: Generating organ-like structures (e.g., "liver buds") with functional integration; engineering hypoimmunogenic iPSCs for universal cell therapy—opening new translational horizons.
  • 「Secretome & Exosomes」: Understanding the role of paracrine signaling in regenerative outcomes and potential cell-free therapeutic strategies.

Why This Book Matters to You

BenefitDescription
「Comprehensive Scholarship」Spans molecular mechanisms, biomaterials, imaging, neurobiology, cardiovascular and bone regeneration, etc.
「Rigorous yet Accessible」Suitable for advanced students and researchers seeking both depth and application.
「Globally Informed」Editors bring diverse, international perspectives and integrative thinking.
「Translational Focus」Prepares readers for bridging bench research with clinical innovation.

In Conclusion

Regenerative Medicine: Emerging Techniques to Translation Approaches is an exceptional scholarly resource that captures the state-of-the-art in regenerative science. With its balanced integration of theory, methodology, and translational ambition, the book serves as both a foundational text and a catalyst for future discovery.

🌱 Whether you are guiding a laboratory project or charting new research directions, this compendium offers both the intellectual rigor and visionary guidance essential for meaningful contributions to regenerative medicine.

You can get E-book via Link

Regenerative Medicine
Regenerative Medicine

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